Biomedical Applications Group

Biomedical Applications Group

Groupmembers:

Dr. Katalin Hideghéty (Group Leader, senior research fellow)

Dr. Tünde Tőkés (research fellow)

Szilvia Brunner (early-stage researcher)

Róbert Polanek (early-stage researcher)

Rita Szabó (early-stage researcher)

 

R&D activity

The Biomedical Application group performs research on potential clinical applications of laser driven ionizing radiation, and on boronated agents both for boron neutron capture therapy, and for boron proton fusion enhanced proton therapy. The medical physics research of our group includes Monte Carlo calculations on laser accelerated high-energy electron beams, and development of chemical dosimetry system appropriate for measurements on high and low LET radiation, on pulsed, ultra-intense particle beams, and physical reactions induced by laser filamentation. We use different in vitro and in vivo models for definition of the relative biological effectiveness of the different RT sources, and we have established the zebrafish embryo model for investigation on radiation modifying agents and on different radiation qualities. The main aim of the research on fish embryos is to develop a highly sensitive biological model for reliable measurements and intercomparison of the effects of laser driven ionizing radiation provided at high-intensity laser facilities.

Publications

E. R. Szabó, I. Plangár, T. Tőkés, I. Mán, R. Polanek, R. Kovács, G. Fekete, Z. Szabó, Zs. Csenki, F. Baska and K. Hideghéty

l-Alpha Glycerylphosphorylcholine as a Potential Radioprotective Agent in Zebrafish Embryo Model

Zebrafish, 13, 481--488, 2016

link

K. Hideghéty, E. R. Szabó, R. Polanek, Z. Szabó, B. Ughy, S. Brunner and T. Tőkés

An evaluation of the various aspects of the progress in clinical applications of laser driven ionizing radiation

J. Instrum., 2017

link

E. Beyreuther, K. Brüchner, M. Krause, M. Schmidt, R. Szabó and J. Pawelke

An optimized small animal tumour model for experimentation with low energy protons

PLOS ONE, 2017

link

K. Hideghéty, R. Szabó, B. Ughy, R. Polanek, Z. Szabó and T. Tőkés

ELI-ALPS ionizáló sugárforrások és orvosbiológiai kutatások és lehetőségek

Magyar Tudomány, 2016

 

link

 

January

23

Wednesday